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Journal article Open Access Scopus Source The journal / series is indexed in Scopus (SCImago list). The article itself has not been verified. 54 Citations Quartil Q2

Detrimental role of prolonged sleep deprivation on adult neurogenesis

Fernandes, C. , Rocha, N.B.F. , Rocha, S. , Herrera-Solís, A. , Salas-Pacheco, J. , García-García, F. , Murillo-Rodríguez, E. , et al
ISLA — Instituto Politécnico de Gestão e Tecnologia
Frontiers in Cellular Neuroscience, Volume 9, Issue APR, 2015
DOI: 10.3389/fncel.2015.00140

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Abstract
Adult mammalian brains continuously generate new neurons, a phenomenon called adult neurogenesis. Both environmental stimuli and endogenous factors are important regulators of adult neurogenesis. Sleep has an important role in normal brain physiology and its disturbance causes very stressful conditions, which disrupt normal brain physiology. Recently, an influence of sleep in adult neurogenesis has been established, mainly based on sleep deprivation studies. This review provides an overview on how rhythms and sleep cycles regulate hippocampal and subventricular zone neurogenesis, discussing some potential underlying mechanisms. In addition, our review highlights some interacting points between sleep and adult neurogenesis in brain function, such as learning, memory, and mood states, and provides some insights on the effects of antidepressants and hypnotic drugs on adult neurogenesis.

Keywords

#adult neurogenesis #sleep deprivation #sleep #hippocampal neurogenesis #subventricular zone #sleep cycles #learning and memory #mood #antidepressants #hypnotics #Neurogenesis #Neuroscience #Sleep (system call) #Hippocampal formation #Psychology

Bibliographic Details

Publication Type Journal article
Publication Year 2015
Journal / Conference / Work Frontiers in Cellular Neuroscience
ISSN 16625102
Volume / Issue Vol. 9 (APR)
Quartile (SCImago) Q2
Scopus Indexing Indexed source (via SCImago)

ISLA Authors & Affiliations

A
Ana Cláudia Moreira Rodrigues
anarodrigues@iscap.ipp.pt ID: 9A13-EB92-244B
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S
Susana Maria de Almeida Correia Aguiar Rocha
srocha@iscap.ipp.pt ID: 1611-C612-F1F0
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